Barely Significant
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PI16 is a shear stress and inflammation-regulated inhibitor of MMP2.

Sci Rep · 2016 · PMC5171773 · PMID 27996045

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extremely significantno p-value reported
It is clear that MMP2 is an extremely significant protease and the identification of PI16 as a novel inhibitor of MMP2 highlights it as a potential regulator of many homeostatic and pathological processes.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.