Assessing QT interval in patients with autoimmune chronic inflammatory diseases: perils and pitfalls.

15 Despite the fact that most of the data strongly suggest that anti-Ro/SSA-mediated electrophysiological effects have a significant clinical impact, some studies reported partially conflicting results (either slight differences but very close to statistical significance, or no association between anti-Ro/SSA and QTc prolongation), both in adults and in children. 14 Notably, even among studies showing a significant association, markedly different percentages of QTc prolongation in patients with anti-Ro/SSA-positive CTD were observed (from ∼10% to 60%). 14 Although

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