Barely Significant
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The Semiosis of "Side Effects" in Genetic Interventions.

Biosemiotics · 2016 · PMC5179580 · PMID 28066514

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possibly significantno p-value reported
6 In both cases, we are in effect talking about the sort of “semiotic scaffolding” (Hoffmeyer 2008 , 2015 ) that biosemiotic researchers recognize as integral to development, where the physical interpretants of past semiosis re-enter into the system as interactants and possibly significant objects in their own right.

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