A Multicenter, Randomized, Open-Label Trial: Efficacy of Once-Daily Versus Twice-Daily Double-Dose Rabeprazole on Refractory Gastroesophageal Reflux Disease-Related Symptoms and Quality of Life.

Curr Ther Res Clin Exp · 2016 · PMC5200872 · PMID 28066515

Europe PMC DOI

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an increasing trendno p-value reported

Although SF-8 scores showed an increasing trend over 8 weeks in both groups, the physical component summaries in the 10 mg BID group significantly improved.

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