Primase is required for helicase activity and helicase alters the specificity of primase in the enteropathogen Clostridium difficile.

Open Biol · 2016 · PMC5204125 · PMID 28003473

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highly significantno p-value reported

The highly significant increase in β-galactosidase activity implies substantial interactions between the C. difficile helicase and putative helicase loader.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.