Among patients requiring multiple levothyroxine dose changes, the estimated cost of managing hypothyroidism escalates to US$4110 per annum, still less than half of the estimated annual cost to treat rheumatoid arthritis or hypertension. CONTROL HE indicates that there may be significant costs associated with excessive exposure to levothyroxine.
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The Economic Impact of Levothyroxine Dose Adjustments: the CONTROL HE Study.
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