Riluzole But Not Melatonin Ameliorates Acute Motor Neuron Degeneration and Moderately Inhibits SOD1-Mediated Excitotoxicity Induced Disrupted Mitochondrial Ca²⁺ Signaling in Amyotrophic Lateral Sclerosis.

Cell viability of SH-SY5Y WT and SH-SY5Y G93A cells in presence of Na-azide for 3 and 30 min leads to a decrease in cell survival (75.0 ± 3.4 and 61.2 ± 6.1% for 3 and 30 min incubation, respectively, for WT; Figure 2B ) and were significantly not different with SOD1 G93A cells (73.5 ± 6.2 and 54.0 ± 8.4% for 3 and 30 min incubation, respectively; Figure 2B ; Table 2 ).

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