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Does an Integrated Care Intervention for COPD Patients Have Long-Term Effects on Quality of Life and Patient Activation? A Prospective, Open, Controlled Single-Center Intervention Study.

PLoS One · 2017 · PMC5218408 · PMID 28060921

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an increasing trendno p-value reported
The HADS-D scores remained stable in the ICG compared with an increasing trend in the UCG.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.