Limb Hypothermia for Preventing Paclitaxel-Induced Peripheral Neuropathy in Breast Cancer Patients: A Pilot Study.

All groups showed highly significant differences: high (Δ t > −2.2°C) vs. moderate cooling (Δ t 2.2–1.5°C) ( p = 0.002); moderate vs. low cooling (Δ t < −1.5°C) ( p = 0.0006) (Figure 6 ).

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