Maternal and child cytokine relationship in early life is not altered by cytokine gene polymorphisms.

Although at the beginning there was a positive trend for association between polymorphism of child's rs13215091 and TNF-α levels (estimate: 0.17; 95% CI: −0.02, 0.37), the direction of association reversed over time with significantly stronger effect exerted by child's decreasing number of minor allele (estimate: −0.01; 95% CI: −0.02, −0.004; Table 2 and Figure 2b ).

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