End-stage cystic fibrosis lung disease is characterised by a diverse inflammatory pattern: an immunohistochemical analysis.

Lymphoid cell and follicle quantification and localization in end-stage CF lung tissue Both cytotoxic T cell (CD8) and CD4 T cell counts were significantly increased in CF tissue compared to controls ( p < 0.001 and p = 0.007, respectively), whereas the slightly increased B cell counts in CF showed only a trend toward significance ( p = 0.091 versus control) (Table 3 , Fig. 2 ).

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