Kidney dysfunction, systemic inflammation and mental well-being in elderly post-myocardial infarction patients.

Moreover, when including all three mental well-being parameters into one statistical model as independent variables with the log-transformed CRP level as the dependent variable, apathy (β = 0.082, p < 0.001) was the only significant correlate, whereas dispositional optimism ( p = 0.40) and the 12-item GDS depression score ( p = 0.36) were not. When testing for interaction, the interaction term for gender × hs-CRP was significant for depression (β = 0.129, p = 0.008), not significant for apathy (β = 0.076, p = 0.12), and of borderline significance for optimism (β = -0.088, p = 0.074).

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