This work is highly significant because it illuminates Bcl-2 as a key survival factor for CML stem cells and the potential of combinations of a Bcl-2 inhibitor and TKIs to eradicate CML stem cells and cure the disease.
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This work is highly significant because it illuminates Bcl-2 as a key survival factor for CML stem cells and the potential of combinations of a Bcl-2 inhibitor and TKIs to eradicate CML stem cells and cure the disease.