C OMPARATIVE S AFETY A NALYSIS OF A LL C ARDIOVASCULAR O UTCOME T RIALS All six CVOTs conducted with incretin-based therapy almost ruled out any real increase in pancreatitis or pancreatic cancer as was perceived earlier; however, there was a slight trend of increase in pancreatitis in DPP-4Is arm compared to the placebo.
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Recent cardiovascular outcome trials of antidiabetic drugs: A comparative analysis.
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SAVOR-TIMI and ELIXA showed a nonsignificant trend in the increase in stroke.