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The most important questions in cancer research and clinical oncology : Question 1. Could the vertical transmission of human papilloma virus (HPV) infection account for the cause, characteristics, and epidemiology of HPV-positive oropharyngeal carcinoma, non-smoking East Asian female lung adenocarcinoma, and/or East Asian triple-negative breast carcinoma?

Chin J Cancer · 2017 · PMC5240210 · PMID 28093081

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a decreasing trendno p-value reported
Early EBV infection appears to be related to socio-economic status and demonstrates a decreasing trend from East Asia through East to West Europe.

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