Rate of NTDs Our results show a highly significant drop in the rate of NTDs in Newfoundland, taking into account all identified affected pregnancies (live births, stillbirths and pregnancies terminated after a prenatal diagnosis of an NTD).
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A comprehensive evaluation of food fortification with folic acid for the primary prevention of neural tube defects.
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The 65% increase in the proportion of women taking vitamin supplements containing folic acid, from 17% in Phase I to 28% in Phase II, suggests that an increasing trend in folic acid supplementation may have played a role in the declining NTD rate in Newfoundland.