Inhibition of Human Drug Transporter Activities by the Pyrethroid Pesticides Allethrin and Tetramethrin.

When a more stringent cut-off value of |r| > 0.92 was applied, 9 molecular descriptors were found to be correlated with OCT1 activity inhibition ( S4 Table ); linear regression analysis next confirmed a highly significant linear relation between the index values of these descriptors and the percentages of OCT1 activity inhibition ( S8 Fig ).

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