According to the company, the Independent Data Monitoring Committee for the COU-AA-302 trial concluded on 27 February 2012 that patients in the AAP arm had a ‘highly significant advantage’, even though the HR for OS had not reached the stringent prespecified statistical significance level (0.0034).
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Abiraterone Acetate for the Treatment of Chemotherapy-Naïve Metastatic Castration-Resistant Prostate Cancer: An Evidence Review Group Perspective of an NICE Single Technology Appraisal.
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