As only a ~20% change in branching is sufficient to alter T cell growth ( Lee et al., 2007 ; Mkhikian et al., 2011 ; Zhou et al., 2014 ), the reduction induced by T H 17 inducing cytokines is highly significant.
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Glycolysis and glutaminolysis cooperatively control T cell function by limiting metabolite supply to N-glycosylation.
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