HIV induces expression of complement component C3 in astrocytes by NF-κB-dependent activation of interleukin-6 synthesis.

J Neuroinflammation · 2017 · PMC5267445 · PMID 28122624

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may be significantno p-value reported

Because astrocytes are the most numerous cells in the brain [ 15 ], their capacity to amplify neuropathogenic effects of HIV-infected macrophages and microglia in this manner may be significant.

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