highly significantp < 0.001
The 3-year DFS rate was 65.6% for all patients, 47.6% and 100% in high and low NEDD9 expression, respectively, and 31.2% and 92.7% in high and low p38 protein expression, respectively, and highly significant inverse relationship was found between 3-year DFS and both high NEDD9 protein expression and high p38 protein expression ( p < 0.001; Table 3 ; Figures 3 and 4 ).