Comparative analysis of secondary structure scores, as assessed by three-state PSI-blast based secondary structure PREDiction (PSIPRED), between KIF13B-C2 861-1,000 and the RPGRIP1N-C2 profile yielded highly significant HHpred probabilities in the range of (97-98) (ref. 28 ), and visual inspection of the aligned sequences indicated near perfect agreement between the predicted secondary structures ( Fig. 2d ), supporting the sequence homology searches.
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KIF13B establishes a CAV1-enriched microdomain at the ciliary transition zone to promote Sonic hedgehog signalling.
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