Brain structure and intragenic DNA methylation are correlated, and predict executive dysfunction in fragile X premutation females.

Transl Psychiatry · 2016 · PMC5290342 · PMID 27959330

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highly significantno p-value reported

42 In this study, highly significant relationships were found between the intragenic methylation within the 5′ end of the FMR1 intron 1 and phenotype measures of executive function, volume of white matter hypointensities and regional cortical thickness in the frontal and parietal cortices of PM females without FXTAS.

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