In terms of prognostic impact, in the overall population, no statistically significant correlation of LDH levels with clinical outcome was evident in PFS (high vs low HR: 1,22 (95% CI: 0.88–1.68), P : 0.232), and a trend towards significance was reported in OS (high vs low HR: 1.35 (95% CI: 0.96–1.88), P : 0.081).
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Serum LDH predicts benefit from bevacizumab beyond progression in metastatic colorectal cancer.
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