Barely Significant
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Depurinized milk downregulates rat thymus MyD88/Akt/p38 function, NF-κB-mediated inflammation, caspase-1 activity but not the endonuclease pathway: in vitro/in vivo study.

Sci Rep · 2017 · PMC5296740 · PMID 28176796

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highly significantno p-value reported
But the role of TGF-β1 in oral tolerance induction was questioned by using a model of TGF-β1 null mice, where it was documented that high oral doses of ovalbumin exhibited highly significant suppression of different lymph node cells, as it intact mice 56 .

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