One-stage individual participant data meta-analysis models: estimation of treatment-covariate interactions must avoid ecological bias by separating out within-trial and across-trial information.

Stat Med · 2017 · PMC5299543 · PMID 27910122

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highly significantno p-value reported

The interaction is −0.011 (95% CI: −0.019 to −0.003; p = 0.004), and thus highly significant, when amalgamating within‐trial and across‐trial information.

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