Alterations in estrogen signalling pathways upon acquisition of anthracycline resistance in breast tumor cells.

PLoS One · 2017 · PMC5308870 · PMID 28196134

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highly significantno p-value reported

However, a strong, highly significant reduction in E2 synthesis was observed upon treatment of empty vector- or AKR1C3 -transfected cells with β-cholanic acid ( Fig 4C ).

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