Barely Significant
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Increase in circulating sphingosine-1-phosphate and decrease in ceramide levels in psoriatic patients.

Arch Dermatol Res · 2017 · PMC5309277 · PMID 27988894

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highly significantno p-value reported
Interestingly, the authors demonstrated highly significant, positive correlation between the percentage reduction of CER synthesis and PASI score in mild and moderate psoriasis.

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