Hotspots of aberrant enhancer activity punctuate the colorectal cancer epigenome.

Nat Commun · 2017 · PMC5309719 · PMID 28169291

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borderline significantno p-value reported

Promoter enrichment was borderline significant, but not to the degree of recurrent or highly recurrent gained VELs.

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highly significantno p-value reported

The highly significant recurrence of these enhancer aberrations suggest that these loci may be under positive selection for acquisition of enhancer function.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.