Copy number variation of human AMY1 is a minor contributor to variation in salivary amylase expression and activity.

There is a highly significant correlation between the two measures ( R = 0.66; P < 0.0001) (Additional file 1 : Figure S4); whilst this is not a strong relationship, it is consistent with previous observations between these two measures ( R = 0.61) [ 6 ].

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This analysis gave marginally non-significant evidence ( P = 0.052) for a difference between the regressions of log protein with even ( R = 0.168) and odd ( R = 0.017) copy numbers (Additional file 1 : Figure S3), suggesting that the relationship between copy number and protein may be different for the odd and even copy numbers.

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