p16<sup>INK4a</sup> , a Senescence Marker, Influences Tenofovir/Emtricitabine Metabolite Disposition in HIV-Infected Subjects.

CPT Pharmacometrics Syst Pharmacol · 2017 · PMC5321809 · PMID 28019088

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marginally significantno p-value reported

Additionally, in the FTC model, age was found to be a marginally significant covariate for central volume of distribution for the parent compound, but was not found to be a significant covariate on drug CL for either TFV or FTC.

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