Long-term treatment with ruxolitinib for patients with myelofibrosis: 5-year update from the randomized, double-blind, placebo-controlled, phase 3 COMFORT-I trial.

In a subgroup analysis by IPSS risk status, there was a nonsignificant trend toward longer OS among patients in the ruxolitinib group compared with the placebo group for both intermediate-2 and high-risk patients (Fig. 5 ).

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