Chemoradiotherapy Versus Radiotherapy Alone in Stage II Nasopharyngeal Carcinoma: A Systemic Review and Meta-analysis of 2138 Patients.

J Cancer · 2017 · PMC5327378 · PMID 28243333

Europe PMC DOI

hedged sentences

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closest p · 0.8× alpha

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boldest claim

The sentences

marginally significantP = 0.04actually significant

Pooling the data assessing OS for 2138 patients from all included studies revealed marginally significant difference between CRT and RT alone (HR = 0.67, 95% CI = 0.45-0.98, P = 0.04) and significant between-study heterogeneity ( P = 0.09).

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marginal significanceP = 0.04actually significant

When it comes to the improved OS for CRT, drawing the conclusion should be discreet because of the marginal significance ( P = 0.04) and obvious between-study heterogeneity.

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