An Exploration of Charge Compensating Ion Channels across the Phagocytic Vacuole of Neutrophils.

Front Pharmacol · 2017 · PMC5329019 · PMID 28293191

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We found no change in vacuolar pH in either model compared to the wild type (WT) or HVCN1 -/- controls ( Figure 7A ), but there was a highly significant decrease in vacuolar area in the HVCN1 -/- /CLIC1 -/- neutrophils; the median decreased from 15.1 μm 2 to 12.8 μm 2 .

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