Barely Significant
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The accuracy of transcranial Doppler in excluding intracranial hypertension following acute brain injury: a multicenter prospective pilot study.

Crit Care · 2017 · PMC5329967 · PMID 28241847

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an increasing trendno p-value reported
In certain situations, such as a drop in CPP, PI presents an increasing trend, which can be related to either increases in ICP or decreases in arterial blood pressure.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.