Optimization for the Production of Deoxynivalenoland Zearalenone by Fusarium graminearum UsingResponse Surface Methodology.

Figure 1 (b1,b2) shows that there was an increasing trend of DON level with increasing incubation time (14–28 days) when other factors were fixed.

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For DON, a highly significant quadratic regression model was obtained with a high F value and a very low p -value ( p = 0.0001 < 0.01), indicating that the combined effects of all the independent variables contributed significantly to maximizing the response [ 34 ].

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