Mucosal delivery of anti-inflammatory IL-1Ra by sporulating recombinant bacteria.

BMC Biotechnol · 2004 · PMC534112 · PMID 15516267

Europe PMC DOI

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highly significantno p-value reported

The reduction of IL-1β-induced fever was more pronounced with lower doses of IL-1β (90% reduction of peak fever induced by 50 ng/kg IL-1β), but it was still highly significant when fever was induced by 100 ng/kg IL-1β (>60% reduction of peak fever) (data not shown).

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