Whole exome sequencing in 75 high-risk families with validation and replication in independent case-control studies identifies TANGO2, OR5H14, and CHAD as new prostate cancer susceptibility genes.

Oncotarget · 2017 · PMC5341753 · PMID 27902461

Europe PMC DOI

hedged sentence

0.0650

closest p · 1.3× alpha

0.0650

boldest claim

The sentences

borderline significantP = 0.065so close (0.05 < p ≤ 0.1)

For overall associations (Table 2 ), HOXB13 p.Gly84Glu was significant (OR = 3.78, 95% CI 1.94 – 8.28; P = 0.0003) and TANGO2 p.Ser17Ter was borderline significant (OR = 1.39, 95% CI 0.98 – 1.99; P = 0.065).

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