Uncovering synthetic lethal interactions for therapeutic targets and predictive markers in lung adenocarcinoma.

Oncotarget · 2016 · PMC5342006 · PMID 27655641

Europe PMC DOI

hedged sentence

0.0520

closest p · 1.0× alpha

0.0520

boldest claim

The sentences

marginal significanceP = 0.052so close (0.05 < p ≤ 0.1)

We found that PARP1 knockdown enhanced carboplatin and pemetrexed-induced cell death in CL1-5 and H1975 cells ( P < 0.05; two sample t-test), except one case had marginal significance (CL1-5 cells treated with 100 nM Pemetrexed having P = 0.052), but not A549 cells.

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