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Prescribing Patterns and Perceptions of Health Care Professionals About Rational Drug use in a Specialist Hospital Clinic.

J Public Health Afr · 2014 · PMC5345410 · PMID 28299123

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an increasing trendno p-value reported
Data on irrational drug use has shown an increasing trend worldwide leading to adverse health consequences.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.