Pentraxin 3 plasma levels at graft-versus-host disease onset predict disease severity and response to therapy in children given haematopoietic stem cell transplantation.

In contrast, when the model considered all available PTX3 readouts which, for patients who developed GvHD, included the measurement at onset, it revealed that PTX3 had indeed a highly significant diagnostic relevance ( p < 0.001), suggesting that the protein level rose at time of GvHD occurrence.

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