Barely Significant
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Effect of tolvaptan on renal water and sodium excretion and blood pressure during nitric oxide inhibition: a dose-response study in healthy subjects.

BMC Nephrol · 2017 · PMC5347830 · PMID 28288570

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highly significantno p-value reported
A highly significant and non-dose dependent 3-fold increase in p-AVP was measured after all three doses of tolvaptan (Fig. 3 ).

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