Hepatocyte specific expression of an oncogenic variant of β-catenin results in cholestatic liver disease.

Oncotarget · 2016 · PMC5349966 · PMID 27895309

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a mild trendno p-value reported

Glutamine synthetase ( Glul ) mRNA levels were 8-fold increased and Cyclin D1 ( Ccnd1 ) mRNA showed a mild trend towards upregulation in Ctnnb1 CA hep mice compared to Cre-negative controls indicating continuous β-catenin signaling and transcription of β-catenin target genes (Figure 1A ).

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