Barely Significant
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Potential mechanisms of effects of serum-derived bovine immunoglobulin/protein isolate therapy in patients with diarrhea-predominant irritable bowel syndrome.

Physiol Rep · 2017 · PMC5350178 · PMID 28275113

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borderline significantno p-value reported
On the other hand, there were numerical (borderline significant) differences in duodenal microbiome with SBI therapy in β diversity and on taxonomic analysis which showed increases in microbial species, specifically Proteobacteria Burkholderiales, Firmicutes Catonella, and unclassified genus organisms.

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