Associations of P16INK4a promoter hypermethylation with squamous intra-epithelial lesion, cervical cancer and their clinicopathological features: a meta-analysis.

Oncotarget · 2017 · PMC5352104 · PMID 27669738

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an increasing trendno p-value reported

Overall, there was an increasing trend of P16 INK4a hypermethylation rates among LSIL (21.4%), HSIL (30.9%) and CC (35.0%) specimens.

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