The changing characteristics and molecular profiles of papillary thyroid carcinoma over time: a systematic review.

Oncotarget · 2017 · PMC5354688 · PMID 27793009

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a decreasing trendno p-value reported

an increasing trendno p-value reported

Our results showed an increasing trend of BRAF and a decreasing trend of RET/PTC prevalence over time in PTCs and classical PTCs, accompanied by an older age of PTC patients, an increase in proportion of PTMC and less aggressive behaviours of tumours.

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