borderline significanceP = 0.092
Furthermore, univariate analysis revealed a favorable PFS for patients with longer TKI-free interval (hazard ratio [HR] 0.48, 95% CI 0.24–0.98, P = 0.044) and a prolonged OS for those with good ECOG performance status (PS) (HR 0.34, 95% CI 0.19–0.61, P < 0.001), and that patients with insertion chemotherapy tended to exhibit better efficacy although only a borderline significance was observed (HR 0.60, 95% CI 0.34–1.09, P = 0.092) (Table 3 ).