Microarray data showing highly significant and reproducible increases in COL3A1 and BGN mRNA levels in IL11Ra -/- uterus were reflected in increased staining intensity for collagen III (Fig. 4A,4B,4C,4D ) and biglycan (Fig. 4E,4F,4G,4H ) in IL11Ra -/- uterus (Fig. 4B,4D,4F,4H ) compared to wild type (Fig. 4A,4C,4E,4G ).
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Uterine extracellular matrix components are altered during defective decidualization in interleukin-11 receptor alpha deficient mice.
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