Similarly, using the gene set enrichment analysis (GSEA) computational method, we obtained a highly significant upregulation of gene sets related to cardiomyocytes, such as “muscle contraction” and “respiratory electron transport” gene sets, and a clear downregulation of the “cycling genes” set ( Figures 2 D and S4 ).
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Notch Inhibition Enhances Cardiac Reprogramming by Increasing MEF2C Transcriptional Activity.
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