As was observed after regional ischaemia, exposure of hearts from young control and DIO rats to 15 min global ischaemia caused a highly significant reduction in aortic output, cardiac output, PSP and Total Work.
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Myocardial susceptibility to ischaemia/reperfusion in obesity: a re-evaluation of the effects of age.
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The sentences
However, although the changes were of borderline significance, middle-aged control hearts appeared to recover better during reperfusion (5/8) than hearts from their young counterparts (3/6).